Mild, Moderate, and Severe Hemophilia – taking all severity levels seriously

Hemophilia A is caused by a deficiency in factor VIII, one of the proteins that helps blood to form clots.  Hemophilia A is classified as mild (5% to <40%), moderate (1% to 5%), or severe (<1%), based on the level of factor VIII protein in the blood. Hemophilia should be taken seriously irrespective of the severity. 

Hemophilia A is caused by a deficiency in factor VIII, one of the proteins that helps blood to form clots.  Hemophilia A is classified as mild (5% to <40%), moderate (1% to 5%), or severe (<1%), based on the level of factor VIII protein in the blood. Hemophilia should be taken seriously irrespective of the severity. 

An infographic depicts severity levels based on Factor VIII protein in the blood: Mild (5%-40%), Moderate (1%-5%), and Severe (<1%), using purple drops of increasing size.

Understanding Mild Hemophilia A

People with mild hemophilia A have factor VIII levels that are 5%-<40%. Mild cases make up around one quarter of all hemophilia A cases. 

People with mild hemophilia A have factor VIII levels that are 5%-<40%. Mild cases make up around one quarter of all hemophilia A cases. 

Mild Hemophilia A Symptoms

Individuals with mild hemophilia typically bleed for prolonged periods following significant trauma or invasive procedures, including dental surgery. Notably, women with mild hemophilia may face challenges such as heavy menstrual bleeding or postpartum hemorrhage.

Individuals with mild hemophilia typically bleed for prolonged periods following significant trauma or invasive procedures, including dental surgery. Notably, women with mild hemophilia may face challenges such as heavy menstrual bleeding or postpartum hemorrhage.

Understanding Moderate Hemophilia A

Moderate hemophilia A, with factor VIII levels at 1-5%, accounts for 15% of the patient population with hemophilia A. 

Moderate hemophilia A, with factor VIII levels at 1-5%, accounts for 15% of the patient population with hemophilia A. 

Moderate Hemophilia A Symptoms

Patients with moderate hemophilia A may experience easy bruising and excessive and prolonged bleeding following injuries causing bleeding, surgeries, dental surgery and occasionally, without any apparent cause. 

Patients with moderate hemophilia A may experience easy bruising and excessive and prolonged bleeding following injuries causing bleeding, surgeries, dental surgery and occasionally, without any apparent cause. 

Understanding Severe Hemophilia A

Severe hemophilia A, marked by factor VIII levels of less than 1%, represents 60% of hemophilia A cases. 

Severe hemophilia A, marked by factor VIII levels of less than 1%, represents 60% of hemophilia A cases. 

Severe Hemophilia A Symptoms

Patients with severe hemophilia A may experience frequent spontaneous bleeds without an apparent cause. Frequent bleeding into joints can lead to chronic pain and joint damage. 

Patients with severe hemophilia A may experience frequent spontaneous bleeds without an apparent cause. Frequent bleeding into joints can lead to chronic pain and joint damage. 

Hemophilia Severity Levels and Management of Bleeds

Hemophilia treatment varies based on the severity of the case. For more serious cases, patients may receive comprehensive care and individualized treatment plans from their healthcare team, including prophylaxis and on-demand treatments, to prevent and manage bleeding episodes effectively. 

Hemophilia treatment varies based on the severity of the case. For more serious cases, patients may receive comprehensive care and individualized treatment plans from their healthcare team, including prophylaxis and on-demand treatments, to prevent and manage bleeding episodes effectively. 

Hemophilia A, regardless of its severity, demands attention and care. It is crucial to recognize the unique challenges faced by people with hemophilia and to continue to advocate its better care and understanding for patients living with this condition. Several treatment options are available for people with hemophilia, enabling them to lead more active lives. 

Hemophilia A, regardless of its severity, demands attention and care. It is crucial to recognize the unique challenges faced by people with hemophilia and to continue to advocate its better care and understanding for patients living with this condition. Several treatment options are available for people with hemophilia, enabling them to lead more active lives. 

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Sanofi Hemophilia Community Relations and Education (CoRe) Managers offer education to people living with hemophilia and their families. CoRe Managers provide information about living with hemophilia and treatment options. Use our handy CoRe Locator to find the CoRe team member nearest you.
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